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European Analysis Of Orphan Drugs: A Journal Article

November 13, 2012

       A journal article from Clinical Pharmacology & Therapeutics, has the objective of, “ ….  quantifying both the sales and volume uptake of orphan drugs in Europe and to assess whether a country’s gross domestic product (GDP) and/or Health Technology Assessment (HTA), influences the orphan drugs’ market uptake …”. 

        Using the IMS Health Database, the study analyzes from 2001 – 2009, the sales and volume uptake for 17 orphan drugs in 23 European countries. The 23 European countries are grouped together based on GDP and the availability of a formal HTA-organization. What the study found is that : 

–  The highest volumes and contributions of orphan drugs in the 1st year happened in European countries with a high GDP (a higher budget for healthcare is implied), regardless of the existence of an HTA-organization

 –  Orphan drugs were less available in countries with a low GDP, when there was a formal HTA-organization. 

       Some statistics from the journal article : 

–  The 3 top European countries for sales of orphan drugs per 100,00 inhabitants are : 

  1. France
  2. Germany
  3. Austria 

–  Between 2001 – 2009, the 3 top European countries that launched the largest # of orphan products are : 

  1. France
  2. UK
  3. Spain. 

        The PubMed citation for this article : 

–      Market uptake of orphan drugs – a European analysis.  Picavet E, Annemans L, Cleemput I, Cassiman D, Simoens S. J Clin Pharm Ther. 2012 Dec;37(6): 664-7. doi: 10.1111/j.1365-2710.2012.01364.x. Epub 2012 Jun 26. PMID: 22731105 [PubMed – in process]. 

Copyright © 2012-2013, Orphan Druganaut Blog.  All rights reserved.

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